Police in Tucson say the search for Nancy Guthrie, the 84-year-old mother of Today co-host Savannah Guthrie, has become a race against time — and some experts warn that the circumstances surrounding her disappearance may make justice especially hard to achieve.

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“We will not rest”

Five days after Nancy vanished from her Tucson home, authorities believe she may have been abducted. No suspects have been publicly identified, and investigators continue to follow leads amid growing concern over her health and safety.

On Wednesday, Savannah appeared alongside family members in an emotional video message, directly addressing whoever may be holding her mother.

“We will not rest,” Savannah said. “Your children will not rest until we are together again.”

She also acknowledged reports of a possible ransom note, urging anyone involved to make contact:

“Please reach out to us.”

Why the suspect may never be found

Despite the intense search, a veteran law-enforcement professional is warning that the odds of identifying the person responsible may be slim — largely because of geography.

Art Del Cueto, a longtime U.S. Customs and Border Protection officer who lives just minutes from Nancy’s home, told Daily Mail that the terrain surrounding the area poses a serious challenge for investigators. Del Cueto is not involved in the case but has years of experience tracking people through southern Arizona’s desert.

The neighborhood sits at the edge of rugged desert land filled with dense cactus, mesquite trees, and rocky ground — conditions that can easily conceal someone trying to escape on foot or by vehicle.

“We’re on the southern border,” Del Cueto said. “You’re dealing with international crime all the time, and there are just too many variables to rule anything out.”

He added that Tucson’s proximity to Mexico complicates matters further.

“If somebody gets spooked, they can make it into Mexico in under an hour and a half. That’s why authorities may not be sharing everything they know.”

According to Del Cueto, this combination of harsh terrain, limited visibility, and international access may explain why law enforcement has been unusually cautious with public details.

Neighbors describe a dangerous landscape

Residents in the Catalina Foothills area have echoed concerns about how unforgiving the environment can be.

A nearby neighbor described the area as deceptively open but extremely difficult to navigate once off the road.

“If you step two feet off the street, you’re basically in the thick of cactus,” the neighbor said. “It’s desert, scrubby mesquite trees, rocks everywhere.”

The neighbor also noted that Nancy uses a cane, making it unlikely she would have wandered into the desert voluntarily.

FBI expert: likely a stranger

Adding another layer to the analysis, former FBI special agent Bryanna Cox, now a criminology professor at the University of South Florida, believes the person responsible is likely unknown to Nancy.

Based on publicly available details, Cox suggested the suspect is probably a man in his 30s or 40s.

“If it were a family member or someone familiar with the home, they wouldn’t have forced entry,” she explained. “If she knew them, they likely would have used a ruse to get her to leave with them.”

Time working against investigators

As days pass, investigators acknowledge that time is critical — and that the environment itself may be undermining their efforts. With desert terrain, destroyed or missing surveillance equipment, and the possibility of a rapid cross-border escape, each hour complicates the path toward answers.

For now, authorities continue to pursue leads, analyze evidence, and urge anyone with information to come forward. Meanwhile, Nancy’s family — and a shaken Tucson community — wait and hope for her safe return.